Product Name:
Human Complement Component 1, S Subcomponent (C1s) ELISA Kit
Cat.#:
JL10351
Regulatory Status:
Alternative:
C1 esterase
Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
3.12-200ng/mL
Sensitivity:
1.6ng/mL
Specificity:
This kit recognizes Human C1S in samples. No significant cross-reactivity or interference between Human C1S and analogues was observed.
Sample Type:
Serum;plasma;tissue homogenates;cell lysates;cell culture supernates and other biological fluids
Assay Procedure:
Research Area:
Immunology
Size & Price: 
Product Datasheets
Instruction: 
| C1S
Complement component 1s ( C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system. C1s is part of the C1 complex. It is encoded by the C1S gene.C1s cleaves C4 and C2, which eventually leads to the production of the classical pathway C3-convertase.
| Repeatability
Intra-assay Precision (Precision within an assay)：CV% < 10%; Inter-assay Precision (Precision between assays)：CV% < 10%| Recovery
The recovery of Human C1S spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.| Sample Type | Range(%) | Average Recovery(%) |
| Serum(n=8) | 84-101 | 96 |
| Plasma(n=8) | 92-105 | 102 |
| Cell Culture Supernates(n=8) | 96-109 | 105 |
| Linearity
Samples were spiked with high concentrations of Human C1S and diluted with Universal Diluent to produce samples with values within the range of the assay.| Serum(n=4) | Plasma(n=4) | Cell Culture Supernates(n=4) | ||
| 1 : 2 | Range (%) | 84-95 | 88-96 | 90-110 |
| Average (%) | 91 | 93 | 95 | |
| 1 : 4 | Range (%) | 89-103 | 87-108 | 105-115 |
| Average (%) | 94 | 98 | 108 |
Related Product
Size
Quantity
Price ($)
48T
1
280 / 280
96T
1
460 / 460